Publications
In Silico Prediction and In Vivo Testing of Promoters Targeting GABAergic Inhibitory Neurons. (2023) Yosuke Niibori, Robert Duba-Kiss, Joseph T. Bruder, Jared B. Smith, and David R. Hampson. Molecular Therapy, Methods and Clinical Development, 28:330-343. doi: 10.1016/j.omtm.2023.01.007. eCollection 2023 Mar 9.PMID: 36874244.
- CNS Dominant Human FMRP Isoform Rescues Seizures, Fear, and Sleep Abnormalities in Fmr1 KO Mice. (2023)Hayes Wong, Alexander W. M. Hooper, Hye Ri Kang, Shiron J. Lee, Jiayi Zhao, Chanchal Sadhu, Satinder Rawat, Steven J. Gray, and David R. Hampson. Journal of Clinical Investigation - Insight doi: 10.1172/jci.insight.169650
- Chapter 50: Gene Therapy and Molecular Interventions. (2022) Alexander W. M. Hooper, Hayes Wong, and David R. Hampson. In: Textbook on Autism Spectrum Disorders, 2nd edition.
- GABAergic Gene Regulatory Elements used in Adeno-associated Viral Vectors. (2021) Robert Duba-Kiss, Yosuke Niibori, and David R. Hampson (2021) Frontiers in Neurology, Special issue: Viral Vector-based Gene Therapy in Neurological Disease: The Future is Now. 2021 Oct 4;12:745159. doi: 10.3389/fneur.2021.745159. eCollection 2021.
- Gene therapy using an orthologue of human fragile X mental retardation protein partially rescues behavioural abnormalities and EEG activity. (2021) Alexander H. W. Hooper, Hayes Wong, Yosuke Niibori, Rozita Abdoli, Subha Karumuthil-Melethil, Chunping Qiao, Olivier Danos, Joseph Bruder, and David R. Hampson (2021) Molecular Therapy Methods and Clinical Development, vol. 22: 196-209. doi: 10.1016/j.omtm.2021.06.013. PMID: 34485605
- Sexually Dimorphic Patterns in Electroencephalography Power Spectrum and Autism-related Behaviors in a Rat Model of Fragile X Syndrome. (2020) Hayes Wong, Alexander W. M. Hooper, Yosuke Niibori, Liang Zhang, Subha Karumuthil-Melethil, Sally M. Till, Peter C. Kind, Olivier Danos, Joseph T. Bruder and David R. Hampson (2020). Neurobiology of Disease, vol. 146, 105118. doi: 10.1016/j.nbd.2020.105118.
- Sexually Divergent Mortality and Partial Phenotypic Rescue after Gene Therapy in a Mouse Model of Dravet Syndrome. (2020) Yosuke Niibori, Shiron J. Lee, Berge A. Minassian, and David R. Hampson (2020). Human Gene Therapy, 31(5-6):339-351. doi: 10.1089/hum.2019.225.
- The Application of Adeno-Associated Viral Vector Gene Therapy to the Treatment of Fragile X Syndrome. (2019) David R. Hampson, Alexander Hooper, and Yosuke Niibori (2019). Brain Science 2019, 9, 32; doi:10.3390/brainsci9020032.
- Identification of a molecular locus for
normalizing dysregulated GABA release from interneurons in the Fragile X
brain. Yang YM,
Arsenault J, Bah A, Krzeminski M, Fekete A, Chao OY, Pacey LK, Wang A,
Forman-Kay J, Hampson DR, Wang LY. (2018) Molecular Psychiatry 2018 Sep
17. doi: 10.1038/s41380-018-0240-0. [Epub ahead of print]
PMID: 30224722 - FMRP Expression Levels in Mouse CNS Neurons Determine Behavioral Phenotype (2016) Jason Arsenault, Shervin Gholizadeh, Yosuke Niibori, Laura K. Pacey, Sebok K. Halder, Enea Koxhioni, Ayumu Konno, Hirokazu Hirai, and David R. Hampson. (2016) Human Gene Therapy 27(12), 982-996 (2016). DOI: 10.1089/hum.2016.090
- Autism Spectrum Disorders and Neuropathology of the Cerebellum. David R. Hampson and Gene J. Blatt. (2015) Frontiers in Neuroscience, published: 06 November 2015 doi: 10.3389/fnins.2015.00420 https://journal.frontiersin.org/article/10.3389/fnins.2015.00420
- Clustering Autism: Using Neuroanatomical Differences in 27 Mouse Models to Gain Insight into the Heterogeneity. Molecular Psychiatry J. Ellegood, E. Anagnostou, B.A. Babineau, J.N. Crawley, L. Lin, M. Genestine, E. DiCicco, D. Bloom, J.K.Y. Lai, J.A. Foster, O. Penagarikano, D.H. Geschwind, L.K. Pacey, D.R Hampson, C.L. Laliberte, G. Horev, A.A. Mills, E. Tam, L.R. Osborne, M. Kouser, F. Espinosa Decerra, Z. Xuan, C.M. Powell, A.Raznahan, D.M. Robins, N. Nakai,J. Nakatani, T. Takumi,M.C.van Eede1, T.M. Kerr,C. Muller, R.D.Blakely, J.Veenstra, D VanderWeele, R.M. Henkelman, and J.P.Lerch. (2015) (Nature Publishing Group) 20(1), 118-25. doi: 10.1038/mp.2014.98. PMID: 25199916
Interregulation between Fragile X Mental Retardation Protein and Methyl CpG Binding Protein 2 (2020) Jason Arsenault, Alexander W. M. Hooper, Shervin Gholizadeh, , Laura K Pacey, Enea Koxhioni, Yosuke Niibori, James H. Eubanks, Lu-Yang Wang, David R. Hampson (2020) . Human Molecular Genetics, 29(23): 3744-3756.